roof·​ie ˈrü-fē How to pronounce roofie (audio)
: a tablet of a powerful benzodiazepine sedative and hypnotic drug C16H12FN3O3 that is not licensed for medical use in the U.S. but is used illicitly

Examples of roofie in a Sentence

Recent Examples on the Web All signs seemed to point to Rufus (Alexander Calvert), the walking, talking psychic roofie, as the culprit. Nick Romano,, 13 Oct. 2023 In part, concerns of a serial killer are fueled by rumors of roofie attacks targeting Rainey Street drinkers. Michael Ruiz, Fox News, 25 Apr. 2023 Meanwhile, concerns of roofie attacks have swirled around the bar scene. Michael Ruiz, Fox News, 1 May 2023 There have been wearable alarm systems, female condoms with teeth, and roofie-detecting nail polish. Jess McHugh, Fortune, 19 Mar. 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'roofie.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


probably by shortening & alteration from Rohypnol, a trademark name for the drug

First Known Use

1994, in the meaning defined above

Time Traveler
The first known use of roofie was in 1994

Dictionary Entries Near roofie

Cite this Entry

“Roofie.” Dictionary, Merriam-Webster, Accessed 20 Jul. 2024.

Medical Definition


roof·​ie ˈrü-fē How to pronounce roofie (audio)
plural roofies
: a tablet of flunitrazepam used illicitly
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