risperidone

noun

ris·​per·​i·​done ri-ˈsper-ə-ˌdōn 

: an antipsychotic drug C₂₈H₂₇FN₄O₂ used especially to treat schizophrenia

Examples of risperidone in a Sentence

Recent Examples on the Web

Maguire has successfully tested risperidone, olanzapine and lurasidone, all of which reduced the severity of stuttering, although none has received approval from the Food and Drug Administration. —Lydia Denworth, Scientific American, 1 Aug. 2021

Some common first-generation antipsychotics include chlorpromazine, haloperidol, perphenazine, and fluphenazine; second-generation drugs include olanzapine, risperidone, quetiapine, aripiprazole, ziprasidone, lurasidone, cariprazine, and paliperidone. —Ashley Abramson, SELF, 11 Feb. 2022

Neither cognitive therapy, nor the antipsychotic drug risperidone (at a low dose) had any effect: those given 'supportive therapy' (basically: sympathetic chats) and a placebo pill did just as well. —Neuroskeptic, Discover Magazine, 16 Dec. 2012

The patient agreed to a risperidone [an antipsychotic] trial of up to 2 mg per day. —Neuroskeptic, Discover Magazine, 19 Feb. 2011

Over the years, Maguire has conducted small, successful clinical studies with these medications including risperidone, olanzapine and lurasidone. —Amber Dance Knowable Magazine, Smithsonian Magazine, 4 Sep. 2020

Her doctor immediately started her on an antidepressant and on risperidone (Risperdal), an antipsychotic. —Andrea Alfano, Scientific American, 1 July 2015

Unlike risperidone, though, aripiprazole has not been shown to work long term in children with autism. —Popular Science, 10 Mar. 2020

For that reason, the drug was expected to cause fewer side effects than risperidone. —Popular Science, 10 Mar. 2020

Word History

Etymology

perhaps from fluor- + is- + piperidine + -one

First Known Use

1988, in the meaning defined above

Medical Definition

risperidone

noun

ris·​per·​i·​done ri-ˈsper-ə-ˌdōn 

: an antipsychotic drug C₂₈H₂₇FN₄O₂ that is used especially to treat schizophrenia, acute manic episodes of bipolar disorder, and irritability associated with autism in children and adolescents

Note: Risperidone's exact mechanism of action is unknown, but it is noted for its affinity for certain serotonin, dopamine, alpha-adrenergic, and histamine receptors in the brain. It is marketed under the trademark Risperdal.