ris·​per·​i·​done | \ ri-ˈsper-ə-ˌdōn How to pronounce risperidone (audio) \

Definition of risperidone

: an antipsychotic drug C28H27FN4O2 used especially to treat schizophrenia

Examples of risperidone in a Sentence

Recent Examples on the Web Over the years, Maguire has conducted small, successful clinical studies with these medications including risperidone, olanzapine and lurasidone. Amber Dance Knowable Magazine, Smithsonian Magazine, 4 Sep. 2020 Her doctor immediately started her on an antidepressant and on risperidone (Risperdal), an antipsychotic. Andrea Alfano, Scientific American, 1 July 2015 Unlike risperidone, though, aripiprazole has not been shown to work long term in children with autism. Popular Science, 10 Mar. 2020 For that reason, the drug was expected to cause fewer side effects than risperidone. Popular Science, 10 Mar. 2020 Antipsychotic medications like haloperidol and risperidone, which are often given for anxiety and agitation, can increase the risk of death in people with dementia. Andrea Petersen, New York Times, 8 Dec. 2019 Instead of confirming that risperidone is linked with birth defects, the study authors note that this is simply something that warrants further investigation. Korin Miller, SELF, 17 Jan. 2019 Research suggests that this is more likely to be an issue with typical antipsychotics than atypical ones, such as olanzapine, clozapine, and aripiprazole—with the exception of risperidone. Kimberly Truong, SELF, 7 Dec. 2018 The second-generation drugs include olanzapine, risperidone, quetiapine, aripiprazole, ziprasidone, lurasidone, cariprazine, and paliperidone. Korin Miller, SELF, 30 Nov. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'risperidone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of risperidone

1988, in the meaning defined above

History and Etymology for risperidone

perhaps from fluor- + is- + piperidine + -one

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The first known use of risperidone was in 1988

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Cite this Entry

“Risperidone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/risperidone. Accessed 2 Dec. 2021.

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More Definitions for risperidone


ris·​per·​i·​done | \ ri-ˈsper-ə-ˌdōn How to pronounce risperidone (audio) \

Medical Definition of risperidone

: an antipsychotic drug C28H27FN4O2 that is used especially to treat schizophrenia, acute manic episodes of bipolar disorder, and irritability associated with autism in children and adolescents

Note: Risperidone's exact mechanism of action is unknown, but it is noted for its affinity for certain serotonin, dopamine, alpha-adrenergic, and histamine receptors in the brain. It is marketed under the trademark Risperdal.


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