ribozyme

noun

ri·​bo·​zyme ˈrī-bə-ˌzīm How to pronounce ribozyme (audio)
: a molecule of RNA that functions as an enzyme (as by catalyzing the cleavage of other RNA molecules)

Examples of ribozyme in a Sentence

Recent Examples on the Web
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And in fact, at the ribozyme level, there’s some real-world overlap, as some ribozymes that were first identified as ligases were converted into polymerases by selecting for this new function. Jonathan M. Gitlin, ArsTechnica, 13 Feb. 2026 The researchers then subjected the pool of ribozymes to a challenge. Quanta Magazine, 25 Aug. 2016 In a truly cooperative system, one ribozyme would speed up the replication of another. Ed Yong, Discover Magazine, 17 Oct. 2012

Word History

Etymology

ribonucleic acid + enzyme

First Known Use

1982, in the meaning defined above

Time Traveler
The first known use of ribozyme was in 1982

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Cite this Entry

“Ribozyme.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ribozyme. Accessed 27 Apr. 2026.

Medical Definition

ribozyme

noun
ri·​bo·​zyme ˈrī-bə-ˌzīm How to pronounce ribozyme (audio)
: a molecule of RNA that functions as an enzyme (as by catalyzing the cleavage of other RNA molecules)

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