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When the infection subsides, pyrogens decrease and the hypothalamus resets the temperature.—Harry Bernheim, The Conversation, 23 May 2025 The immune system responds by releasing molecules called pyrogens, which induce fever.—Harry Bernheim, The Conversation, 23 May 2025 Twenty-two participants either got a shot that included a pyrogen — an agent found in bacteria such as E. coli that causes fevers — or a placebo.—Jennifer Walter, Discover Magazine, 29 Dec. 2020
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