protease inhibitor

noun

Definition of protease inhibitor

: a substance that inhibits the action of a protease specifically : any of various drugs (such as indinavir) that inhibit the action of the protease of HIV so that the cleavage of viral proteins into mature functional infectious particles is prevented and that are used especially in combination with other agents in the treatment of HIV infection

Examples of protease inhibitor in a Sentence

Recent Examples on the Web Pfizer’s oral treatment, Paxlovid, also is a protease inhibitor. Mike Freeman, San Diego Union-Tribune, 27 Dec. 2021 Enlarge / Scenes like this might become less common if a new SARS-CoV-2 protease inhibitor becomes widely available. John Timmer, Ars Technica, 15 Dec. 2021 Paxlovid is a type of protease inhibitor that works to disrupt the process by which SARS-CoV-2 makes copies of itself in the body. Alexander Tin, CBS News, 14 Dec. 2021 Paxlovid, by contrast, is a protease inhibitor, much like those developed to combat HIV. Stephani Sutherland, Scientific American, 1 Dec. 2021 Paxlovid, on the other hand, uses an experimental molecule called PF-07321332 that works as a protease inhibitor, as CNBC explains. Colleen Stinchcombe, SELF, 30 Nov. 2021 The Pfizer drug, PF-07321332, is a protease inhibitor and when combined with a low dose of the HIV/AIDS drug, (ritonavir trade name Paxlovid) persists longer in the human body, making the combination more effective in fighting a virus. Steve Brozak, Forbes, 8 Nov. 2021 Paxlovid is a protease inhibitor – the same type of drug that turned HIV into a manageable disease – which blocks replication of the virus. Karen Weintraub, USA TODAY, 6 Nov. 2021 Paxlovid is a protease inhibitor, a type of antiviral medication that has been successfully used for diseases such as HIV and Hepatitis C. Alex Knapp, Forbes, 5 Nov. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'protease inhibitor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of protease inhibitor

1943, in the meaning defined above

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Time Traveler for protease inhibitor

Time Traveler

The first known use of protease inhibitor was in 1943

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Dictionary Entries Near protease inhibitor

protease

protease inhibitor

protea veld

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Last Updated

12 Jan 2022

Cite this Entry

“Protease inhibitor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/protease%20inhibitor. Accessed 18 Jan. 2022.

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More Definitions for protease inhibitor

protease inhibitor

noun

Medical Definition of protease inhibitor

: a substance that inhibits the action of a protease specifically : any of various drugs (as indinavir or saquinavir) that inhibit the action of HIV protease so that cleavage of viral proteins into mature infectious particles is prevented and that are used especially in combination with other antiretroviral agents in the treatment of HIV infection

More from Merriam-Webster on protease inhibitor

Britannica.com: Encyclopedia article about protease inhibitor

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