prostate-specific antigen

pros·​tate-spe·​cif·​ic antigen

Definition of prostate-specific antigen

: a protease secreted by epithelial cells of the prostate gland that is used in the diagnosis of prostate cancer since its concentration in blood serum tends to be proportional to the clinical stage of the disease abbreviation PSA

Examples of prostate-specific antigen in a Sentence

Recent Examples on the Web Within six months, his prostate-specific antigen, the protein secreted by cancer cells that oncologists use to measure a patient’s cancer, went down to zero, his bone lesions mostly disappeared, and Olson started to feel like his old self again. Sarah Elizabeth Richards, Wired, "One Man’s Search for the DNA Data That Could Save His Life," 19 Nov. 2020 Al's diagnosis came about after a routine physical yielded an elevated prostate-specific antigen (PSA) in his bloodwork. Kayla Keegan, Good Housekeeping, "'Today' Star Hoda Kotb Posts a Heartfelt Instagram After Al Roker's Prostate Cancer Diagnosis," 7 Nov. 2020 That's why 16 years ago Arkansas Urology set out to make prostate-specific antigen (PSA) screens easy and free to any patient who walks through our doors. Arkansas Online, "OPINION | TIMOTHY LANGFORD: Get screened," 12 Sep. 2020 That may be because many doctors pulled back on using the controversial prostate-specific antigen test, or PSA, which can spot the disease but can lead to over-treatment of men who may never have died from their tumors, Siegel said. Robert Langreth,, "U.S. Cancer Death Rates Are Dropping at the Fastest Pace on Record," 5 May 2020 There’s precedent, like the rollout of the prostate-specific antigen (PSA) blood test in the US and Europe in the 1980s. Annabelle Timsit, Quartz, "“As important as finding the cure to cancer”: Behind the effort to end childhood toxic stress," 21 Mar. 2020 One is the 4Kscore test that combines the levels of four prostate-specific antigens with clinical information to estimate a man’s risk of having an aggressive cancer. New York Times, "Debating the Value of PSA Prostate Screening," 24 Feb. 2020 Caught early, through either a digital rectal exam (DRE) or a prostate-specific antigen (PSA) blood test, this disease is nearly always curable. Armin Brott,, "How to save your husband’s life," 22 Nov. 2019 Because mammography, prostate-specific antigen levels and all other initial testing for common cancers are merely screening tests, no patient ever receives definitive treatment for cancer before these tests are confirmed by a biopsy. Scientific American, "Readers Respond to "The Coming Mega Drought" and Other Articles," 1 May 2012

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'prostate-specific antigen.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of prostate-specific antigen

1979, in the meaning defined above

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The first known use of prostate-specific antigen was in 1979

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Last Updated

30 Nov 2020

Cite this Entry

“Prostate-specific antigen.” Dictionary, Merriam-Webster, Accessed 16 Jan. 2021.

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More Definitions for prostate-specific antigen

prostate-specific antigen


Medical Definition of prostate-specific antigen

: a protease that is secreted by the epithelial cells of the prostate and is used in the diagnosis of prostate cancer since its concentration in the blood serum tends to be proportional to the clinical stage of the disease abbreviation PSA

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