pros·​ta·​glan·​din | \ ˌprä-stə-ˈglan-dən How to pronounce prostaglandin (audio) \

Definition of prostaglandin

: any of various oxygenated unsaturated cyclic fatty acids of animals that are formed chiefly by the action of cyclooxygenase on arachidonic acid and perform a variety of hormonelike actions (as in controlling blood pressure or smooth muscle contraction)

Examples of prostaglandin in a Sentence

Recent Examples on the Web Specifically, NSAIDs blocks two enzymes, COX-1 and COX-2, that are necessary for prostaglandins to form. Sarah Jacoby, SELF, "Can You Use Ibuprofen to Manage Coronavirus Symptoms?," 24 Apr. 2020 This process involves washing it to remove unwanted substances like non-motile sperm, white blood cells and prostaglandins (hormone-like chemicals that can cause painful cramping when deposited into the uterus). Christina Caron, New York Times, "Getting Pregnant With IUI: What You Need to Know," 18 Apr. 2020 The concentration of prostaglandins in semen may be too low to affect the cervix, Dr. Schaffir said. Melinda Wenner Moyer, New York Times, "Does Anything Actually Make You Go Into Labor?," 16 Apr. 2020 The pain comes from prostaglandins, chemical compounds produced during the ovulation cycle, which can cause cramps as the muscle of the uterus — the myometrium — squeezes down to get the blood out. Perri Klass, New York Times, "Helping Teenagers With Menstrual Pain," 3 Feb. 2020 Endometriosis lesions of any size can release varying levels of prostaglandins or cytokines (chemicals associated with pain), Dr. Hornstein says. Cassie Shortsleeve, SELF, "What Exactly Are the Stages of Endometriosis?," 25 Sep. 2019 This results in the reduction of prostaglandins, which play a key role in pain and inflammation., "NSAIDs: How dangerous are they for your heart?," 23 Oct. 2019 The thinking is that activity in certain nerve cells makes blood vessels in your brain dilate and also causes a release of inflammatory substances like prostaglandins, which can create pain. Korin Miller, SELF, "9 Health Issues That Can Cause Sensitivity to Light," 5 June 2018 Ibuprofen lowers your levels of prostaglandins, which are the hormone-like substances that trigger uterine cramping and cause pain and inflammation. Kara Wahlgren, Seventeen, "8 Ways to Make Your Cramps Suck Less," 6 Sep. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'prostaglandin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of prostaglandin

1936, in the meaning defined above

History and Etymology for prostaglandin

prostate gland + -in entry 1; from its occurrence in the seminal fluid of animals

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Time Traveler for prostaglandin

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The first known use of prostaglandin was in 1936

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Cite this Entry

“Prostaglandin.” Dictionary, Merriam-Webster, Accessed 20 Jan. 2021.

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pros·​ta·​glan·​din | \ ˌpräs-tə-ˈglan-dən How to pronounce prostaglandin (audio) \

Medical Definition of prostaglandin

: any of various oxygenated unsaturated cyclic fatty acids of animals that are formed as cyclooxygenase metabolites especially from unsaturated fatty acids (as arachidonic acid) composed of a chain of 20 carbon atoms and that perform a variety of hormonelike actions (as in controlling blood pressure or smooth muscle contraction)

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