pip·​er·​ine ˈpi-pə-ˌrēn How to pronounce piperine (audio)
: a white crystalline alkaloid C17H19NO3 that is the chief active constituent of pepper

Example Sentences

Recent Examples on the Web To ensure users get the most out of every ingredient, the Leanbean formula includes piperine, a black pepper extract known for its ability to boost bioavailability. Dallas News, 26 Aug. 2022 Bioperine, or piperine, is a black pepper extract that assists in absorption. Dallas News, 12 Jan. 2023 Additionally, piperine may prevent mental impairment related to Alzheimer’s disease. Amber Smith, Discover Magazine, 17 Oct. 2022 This fat-busting blend consists of capsicum, piperine, caffeine, and niacin (vitamin B3). Amber Smith, Discover Magazine, 4 Dec. 2022 Because the fruit has been stripped of its outer layer of flesh, which contains the piperine compound, white peppercorns are not as peppery. Washington Post, 11 Feb. 2022 But research has linked piperine — the active compound in black pepper — to better absorption of curcumin in your body (specifically an increase of 2000% in the bioavailability of curcumin). Stefani Sassos, Ms, Rdn, Cso, Good Housekeeping, 22 Apr. 2021 Peppers—including black pepper and chilli pepper—which contain a substance called piperine that irritates nasal passages. Rebecca Strong, Health.com, 17 Feb. 2022 This layer, along with the surface layers of the seed within, contains the main compound responsible for the spice’s characteristic pungent flavor: piperine. Washington Post, 11 Feb. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'piperine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


probably from French pipérine, from Latin piper pepper

First Known Use

1820, in the meaning defined above

Time Traveler
The first known use of piperine was in 1820

Dictionary Entries Near piperine

Cite this Entry

“Piperine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/piperine. Accessed 2 Feb. 2023.

Medical Definition


pip·​er·​ine ˈpip-ə-ˌrēn How to pronounce piperine (audio)
: a white crystalline alkaloid C17H19NO3 that is the chief active constituent of pepper

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