1
: a system of betting (as on horse races) in which the bettor must pick the winners of six consecutive races
… is one of 42 individuals holding the 78 tickets that legitimately had five out of six winners in the Breeders' Cup pick-six wager.—Bill Finley
2
American football : an interception returned by the intercepting team for a touchdown
By halftime he had thrown two interceptions—the second a 69-yard pick-six to outside linebacker and Most Valuable Player Malcolm Smith …—S. L. Price

Examples of pick-six in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Trotter ranks third among rookies with 62 tackles and has a pick-six against the Cincinnati Bengals’ Joe Burrow along with one sack and three pass breakups. — Brad Biggs, Chicago Tribune, 8 Nov. 2026 Backup Cole Ballard, who battled Marshall for KU’s starting quarterback position during the preseason completed 20 of 38 passes for 285 yards, a touchdown and a pick-six interception in a 22-16 road defeat. — Gary Bedore, Kansas City Star, 5 Nov. 2026 While everybody will focus on the pick-six, Carroll said the goal-line stand is really what changed the tone of the game. — Steven Johnson, Fort Worth Star-Telegram, 1 Nov. 2026 Dunnigan is second on the team with 28 tackles and has one sack, one forced fumble, one fumble recovery and one interception — a pick-six against Clemson. — Adam Lichtenstein, Sun Sentinel, 29 Oct. 2026 See All Example Sentences for pick-six

Word History

First Known Use

1980, in the meaning defined at sense 1

Time Traveler
The first known use of pick-six was in 1980

Browse Nearby Words

Cite this Entry

“Pick-six.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/pick-six. Accessed 14 Nov. 2026.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!