Definition of pick–six
1 : a system of betting (as on horse races) in which the bettor must pick the winners of six consecutive races … is one of 42 individuals holding the 78 tickets that legitimately had five out of six winners in the Breeders' Cup pick-six wager. — Bill Finley
2 football : an interception returned by the intercepting team for a touchdown By halftime he had thrown two interceptions—the second a 69-yard pick-six to outside linebacker and Most Valuable Player Malcolm Smith … — S. L. Price
First Known Use of pick–six
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