phosphorothioate
noun
phos·pho·ro·thio·ate
ˌfäs-fə-rō-ˈthī-ō-ˌāt 
: an oligonucleotide in which the oxygen atom normally linking two consecutive nucleotides has been replaced with sulfur and which resists degradation by cellular enzymes compare phosphodiester
Cite this Entry
“Phosphorothioate.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/phosphorothioate. Accessed 1 Dec. 2025.
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