pheochromocytoma

noun
pheo·​chro·​mo·​cy·​to·​ma | \ ˌfē-ə-ˌkrō-mə-sə-ˈtō-mə How to pronounce pheochromocytoma (audio) , -sī- \
plural pheochromocytomas or less commonly pheochromocytomata\ ˌfē-​ə-​ˌkrō-​mə-​sə-​ˈtō-​mə-​tə How to pronounce pheochromocytoma (audio) , -​sī-​ \

Definition of pheochromocytoma

: a tumor that is derived from chromaffin cells and is usually associated with paroxysmal or sustained hypertension Pheochromocytoma is a rare cause of hypertensive crisis. The hypertension may be either sustained or paroxysmal, with episodes of headache, diaphoresis, palpitations, anxiety, nausea, vomiting, and abdominal pain.— David A. Calhoun et al.

called also pheo

Examples of pheochromocytoma in a Sentence

Recent Examples on the Web The vast majority of people who experience a racing heart and debilitating headaches don’t actually have a pheochromocytoma. Lisa Sanders, New York Times, 30 Oct. 2019 The most likely cause of that result was a rare tumor called a pheochromocytoma. Lisa Sanders, New York Times, 30 Oct. 2019 The rare cancer in question is called pheochromocytoma. Madeline Mcgee, Anchorage Daily News, 15 July 2019 Lisa Sanders’s pheochromocytoma case study made me weep. New York Times, 23 June 2017 Donations in memory of Jessica Lum may be made to find a cure for pheochromocytoma. Pete Brook, WIRED, 17 July 2013 Individuals can have more adrenaline than normal in times of physical or psychological stress, but levels this high strongly suggested that the patient had an adrenaline-producing tumor known as a pheochromocytoma or pheo. Lisa Sanders, M.d., New York Times, 7 June 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'pheochromocytoma.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of pheochromocytoma

1920, in the meaning defined above

History and Etymology for pheochromocytoma

borrowed from German Phäochromocytom, from Phäochromocyte "chromaffin cell" (from phäochrom "chromaffin" —from Greek phaiós "a shade between black and white, gray, dark gray" [of obscure origin] + German -chrom -chrome— + -o- -o- + -cyte -cyte) + -om -oma

Note: The term was introduced by the German pathologist Ludwig Pick (1868-1944) in "Das Ganglioma embryonale sympathicum (Sympathoma embrionale)," Berliner klinische Wochenschrift, 49. Jahrgang, Nr. 1 (January 1, 1912), p. 21/2. Pick paraphrases phäochrom as chrombraun, suggesting that phäo- is taken to mean braun "brown." This somewhat misleading reading of the Greek word goes back to the original use of phäochrom, by the anatomist Heinrich Poll, in an account of the developmental history of the adrenal glands in vertebrates ("Die vergleichende Entwickelungsgeschichte der Nebennierensysteme der Wirbeltiere," chapter two, part two of Handbuch der vergleichenden und experimentellen Entwickelungslehre der Wirbeltiere, edited by Oskar Hertwig, 3. Band, 1. Teil, p. 444). In discussing cells from the medulla of the adrenal glands, which turn a bright yellow to dark brown when treated with chromium salts ("eine intensive hellgelbe bis dunkelbraune Färbung"), Poll says the following: "Diese Eigenschaft entdeckte Jakob Henle im Jahre 1865, Stilling (1890) nannte die Zellen chromophil, Kohn (1898) neuerdings chromaffin: eindeutig und einsprachig können sie als phäochrome [footnote: "von φαιός = braun, und dem Namen des Elements „Chrom".], deutsch etwa als chrombraune Zellen bezeichnet werden." ("This property was discovered by Jakob Henle in 1865, Stilling (1890) named the cells chromophil, Kohn (1898) more recently chromaffin: the cells can be designated unambiguously and using a single language [i.e., Greek] as pheochrome [footnote: "from phaiós = brown, and the name of the element chromium"], in German approximately as chrome-brown.") Though "braun" is given as a possible translation of Greek phaiós in, for example, Franz Passow's widely used Handwörterbuch der griechischen Sprache (5th edition, 1857), the fuller characterization is "schummrig, dämmerig, zwischen Licht und Dunkel, daher von jeder Farbe zwischen schwarz und weiss, schwärzlich, schwarzgrau, grau, braun" ("dusky, twilight, between light and dark, hence of every color between black and white, blackish, gray-black, gray, brown").

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The first known use of pheochromocytoma was in 1920

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Dictionary Entries Near pheochromocytoma

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Cite this Entry

“Pheochromocytoma.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/pheochromocytoma. Accessed 3 Dec. 2021.

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More Definitions for pheochromocytoma

pheochromocytoma

noun
pheo·​chro·​mo·​cy·​to·​ma
variants: or British phaeochromocytoma \ ˌfē-​ə-​ˈkrō-​mə-​sə-​ˈtō-​mə, -​sī-​ How to pronounce pheochromocytoma (audio) \
plural pheochromocytomas also pheochromocytomata\ -​mət-​ə How to pronounce pheochromocytoma (audio) \

Medical Definition of pheochromocytoma

: a tumor that is derived from chromaffin cells and is usually associated with paroxysmal or sustained hypertension Pheochromocytoma is a rare cause of hypertensive crisis. The hypertension may be either sustained or paroxysmal, with episodes of headache, diaphoresis, palpitations, anxiety, nausea, vomiting, and abdominal pain.— David A. Calhoun et al.

called also pheo

More from Merriam-Webster on pheochromocytoma

Britannica.com: Encyclopedia article about pheochromocytoma

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