penetrance

noun
pen·​e·​trance | \ ˈpe-nə-trən(t)s How to pronounce penetrance (audio) \

Definition of penetrance

: the proportion of individuals of a particular genotype that express its phenotypic effect in a given environment

Examples of penetrance in a Sentence

Recent Examples on the Web Sema4 only reports results for diseases that have a greater than 80 percent penetrance—the proportion of people with a genetic variant who end up developing the disease. Tanya Lewis, Scientific American, 24 Dec. 2019 The clues are all there: People in countries with a greater Internet penetrance report lower empathy. Jamil Zaki, Scientific American, 6 Aug. 2019 Research suggests that random fluctuations in gene activity could explain some instances of the phenomenon, known as partial penetrance, which likely plays a role in some human diseases. Quanta Magazine, 22 May 2014

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'penetrance.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of penetrance

1934, in the meaning defined above

History and Etymology for penetrance

International Scientific Vocabulary, from Latin penetrare

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Time Traveler for penetrance

Time Traveler

The first known use of penetrance was in 1934

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Statistics for penetrance

Cite this Entry

“Penetrance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/penetrance. Accessed 24 Jul. 2021.

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More Definitions for penetrance

penetrance

noun
pen·​e·​trance | \ ˈpen-ə-trən(t)s How to pronounce penetrance (audio) \

Medical Definition of penetrance

: the proportion of individuals of a particular genotype that express its phenotypic effect in a given environment — compare expressivity

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