Definition of open up
1 : to make available or possible The discovery opens up the possibility of new cures.
2 : to make plain or visible : disclose
3 : to open by cutting into
1 : to become available or possible The hostess will let us know when a table opens up.
2 : to spread out or come into view The road opens up ahead.
3 : to commence firing
4 : to become communicative tried to get the patient to open up
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