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open reading frame

noun

open read·​ing frame -ˈrēd-iŋ- How to pronounce open reading frame (audio)
: a reading frame that does not contain a nucleotide triplet which stops translation before formation of a complete polypeptide
abbreviation ORF

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Cite this Entry

“Open reading frame.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/open%20reading%20frame. Accessed 27 Nov. 2025.

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