on the brain

idiom

informal
: always in one's thoughts
I've had pizza on the brain all day.
He's got sex on the brain.

Examples of on the brain in a Sentence

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Scientists have long known that arsenic in drinking water is a health threat, but its affects on the brain were less clear. Austin Corona, AZCentral.com, 30 Aug. 2025 PetMD experts say that dogs who experience cognitive dysfunction have a buildup of protein known as beta-amyloid that forms plaques on the brain. Alyce Collins, MSNBC Newsweek, 20 Aug. 2025 However, on the opposite end, the study showed signs of a possible detrimental effect on the brain when people had high B12 levels in their blood. Perri Ormont Blumberg, Time, 13 Aug. 2025 Antipsychotic agents have traditionally focused on the brain’s dopamine system, blocking type 2 dopamine (D2) receptors. New Atlas, 11 Aug. 2025 See All Example Sentences for on the brain

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“On the brain.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/on%20the%20brain. Accessed 8 Sep. 2025.

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