obstacle
noun
                                                                                                                            
                                                            ob·sta·cle
                    
                                                                                                              
                                                                                                                                  ˈäb-sti-kəl 
                                                                                                                              
            -ˌsti-
                                                      
                                                          
                                
              
          
                                                      : something that impedes progress or achievement                                      
              
                             
Mosquitoes were a great obstacle to the building of the Panama Canal.
                                       … elders … often facing daily medical, social, and psychological obstacles.—
Vicki Bloom and B. B. Green-Field
                         
                
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  Merriam-Webster unabridged




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