: a monoamine C8H11NO3 that is a neurotransmitter in postganglionic neurons of the sympathetic nervous system and in some parts of the central nervous system, is a vasopressor hormone of the adrenal medulla, and is a precursor of epinephrine in its major biosynthetic pathway

Examples of norepinephrine in a Sentence

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Clozapine also has complex interactions with other neurotransmitter pathways, including those involving acetylcholine, histamine, and norepinephrine, which contribute to its pharmacological and toxicity profile. — Encyclopedia Britannica, 7 Oct. 2026 These prescription stimulants can sharpen focus by prompting the brain to release more neurotransmitters such as dopamine and norepinephrine, which play an important role in the body’s fight-or-flight response. — Jen Christensen, CNN Money, 29 Aug. 2026 The brain's locus coeruleus, regulating norepinephrine, governs cognitive performance. — Julian Hayes Ii, Forbes.com, 23 Aug. 2026 Research also suggests changes in brain chemistry involving neurotransmitters such as serotonin, dopamine and norepinephrine can cause depressive symptoms. — Sara Moniuszko, USA Today, 30 June 2026 See All Example Sentences for norepinephrine

Word History

First Known Use

1937, in the meaning defined above

Time Traveler
The first known use of norepinephrine was in 1937

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Cite this Entry

“Norepinephrine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/norepinephrine. Accessed 10 Oct. 2026.

Kids Definition

norepinephrine

noun
: a hormone that causes blood vessels to contract and helps to transmit nerve impulses in the sympathetic nervous system and in some parts of the central nervous system

Medical Definition

: a catecholamine C8H11NO3 that is the chemical means of transmission across synapses in postganglionic neurons of the sympathetic nervous system and in some parts of the central nervous system, is a vasopressor hormone of the adrenal medulla, and is a precursor of epinephrine in its major biosynthetic pathway

called also arterenol, noradrenaline

see levophed

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