: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
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The pouches also closely resemble nicotine products, raising concerns among school officials about student health and the difficulty of distinguishing between the products. — ABC News, 22 Oct. 2026 Nootropic pouches have moved from fringe biohacker product to full wellness-aisle fixture, pitched as a nicotine-free, caffeine-forward answer to the morning coffee ritual. — Hanna Wickes, Kansas City Star, 20 Oct. 2026 But while most fans assumed that the bulk of the changes were a result of her chronic autoimmune disease, Gomez revealed for the first time that the change in her voice is a result of heavy nicotine use. — Isabella Albaig, Vulture, 19 Oct. 2026 Gomez, 34, explained her own nicotine habit left her voice forever changed in a warning given to fans. — Lauryn Overhultz, FOXNews.com, 19 Oct. 2026 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 24 Oct. 2026.

Kids Definition

nicotine

noun
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

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