Definition of muffuletta
: a sandwich made with round Italian bread and filled usually with cold cuts, cheese, and olive salad The muffuletta is one of the great sandwiches of New Orleans.
Origin and Etymology of muffuletta
probably from Italian dialect, from Italian muffoletta little muff, diminutive of muffola muff, from French moufle, from Medieval French
First Known Use: 1967
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