monoamine

noun

mono·​amine ˌmä-nō-ə-ˈmēn 

: an amine RNH₂ that has one organic substituent attached to the nitrogen atom

especially : one (such as serotonin) that is functionally important in neural transmission

Examples of monoamine in a Sentence

Recent Examples on the Web

These are vesicular monoamine transporter-2 inhibitors. —Bruce Y. Lee, Forbes.com, 15 May 2025

Ketamine therapy for depression Still, not everyone benefits from drugs that work on monoamines. —Sonya Collins, Fortune Well, 4 Nov. 2023

The history of antidepressants Most antidepressants aim for the same target: the monoamine system. —Sonya Collins, Fortune Well, 4 Nov. 2023

These depletion techniques, given separately, are known to cause temporary relapses in about 50% of people who've responded to antidepressants targeting the corresponding monoamine, and also in some people who used to be depressed but are no longer taking medication. —Neuroskeptic, Discover Magazine, 5 June 2010

Then, psychiatrists found that many people, like Attardo, did not respond to monoamine antidepressants. —Claudia López Lloreda, STAT, 17 Aug. 2021

The monoamine hypothesis came about by serendipity. —Claudia López Lloreda, STAT, 17 Aug. 2021

Word History

Etymology

International Scientific Vocabulary

First Known Use

1951, in the meaning defined above

Phrases Containing monoamine

• monoamine oxidase

Rhymes for monoamine

• acetylene
• adenosine
• amphetamine
• anthropocene
• antipyrine
• apomorphine
• apoprotein
• aquamarine
• arsphenamine
• azobenzene
• buprenorphine
• chlorobenzene

Medical Definition

monoamine

noun

mono·​am·​ine ˌmän-ō-ə-ˈmēn  -ˈam-ˌēn 

variants also monamine

ˌmän-ə-ˈmēn  -ˈam-ˌēn 

: an amine RNH₂ that has one organic substituent attached to the nitrogen atom

especially : one (as serotonin) that is functionally important in neural transmission