misc

1 of 2

abbreviation

miscellaneous

MIS-C

2 of 2

abbreviation or noun

ˌem-ˌī-ˌes-ˈsē 

ˈmis-ˈsē

: multisystem inflammatory syndrome in children

The features of MIS-C include signs that the blood vessels and organs are irritated or inflamed.

—Elaine Cox

The syndrome appears to be rare, but the Centers for Disease Control and Prevention—which recently dubbed the condition MIS-C or multisystem inflammatory syndrome in children—has expressed alarm about the rapid decline of patients with the illness.

—Ariana Eunjung Cha and Chelsea Janes

Word History

First Known Use

Abbreviation Or Noun

2020, in the meaning defined above

Medical Definition

MIS-C

abbreviation or noun

ˌem-ˌī-ˌes-ˈsē 

ˈmis-ˈsē

: multisystem inflammatory syndrome in children

The medical condition, known as multisystem inflammatory syndrome in children, or MIS-C, is a rare but potentially deadly medical condition typically affecting multiple organs—including the heart, kidneys, brain, among others—that has been detected in children or young adults up to 21 years of age who are believed to have had COVID-19 or been exposed to it, according to the federal Centers for Disease Control.

—Andy East, The Republic (Columbus, Indiana)

Most children with MIS-C have persistent high fevers for three or more days, but then exhibit a range of symptoms in various combinations reflecting inflammation in multiple organs of the body.

—Sandra L. Fenwick, The Boston Globe