midlife

noun

mid·​life ˈmid-ˈlīf 

: middle age

midlife adjective

Examples of midlife in a Sentence

changes that occur at midlife

Recent Examples on the Web

Melinda French Gates has pledged more than $600 million to women’s health over the past two years, with $215 million of that earmarked for midlife and menopause care and training. — Yulin Hswen, STAT, 27 Aug. 2026

This is key for women in midlife because resistance training, or pushing against something, builds and preserves strong bones and muscles. — Helen Carefoot, Flow Space, 26 Aug. 2026

The brain may undergo a notable shift at midlife, as new research suggests that its protective immune cells begin to decline and are increasingly replaced by inflammatory cells at around age 50. — Melissa Rudy, FOXNews.com, 25 Aug. 2026

But much of the brain-imaging research has looked at women around midlife and measured their brains at one point in time. — Emily Kay Votruba, EverydayHealth.com, 25 Aug. 2026

Word History

First Known Use

1807, in the meaning defined above

Phrases Containing midlife

• midlife crisis

Rhymes for midlife

• alewife
• birdlife
• folklife
• housewife
• jackknife
• midwife
• nightlife
• penknife
• wildlife
• afterlife
• pocketknife
• knife

Kids Definition

midlife

noun

mid·​life ˈmid-ˈlīf 

: middle age

midlife adjective

Medical Definition

midlife

noun

mid·​life

(ˈ)mid-ˈlīf

: middle age