meth·​am·​phet·​amine ˌme-tham-ˈfe-tə-ˌmēn How to pronounce methamphetamine (audio)
: a synthetic or semisynthetic compound C10H15N that stimulates the central nervous system, is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit disorder and obesity, and that is often abused illicitly for its stimulant properties
methamphetamine is a powerful addictive stimulant whose longtime consumers tend to suffer from paranoia, depression, hallucinations, and violent rages.William Finnegan

called also meth, methedrine, speed

compare crystal meth

Examples of methamphetamine in a Sentence

Recent Examples on the Web Rudd was convicted of two drug offenses in March — including the possession of methamphetamine — and was on a year’s supervised release, according to the Kentucky Department of Corrections. Michael Dorgan, Fox News, 7 June 2024 On June 30, 2021, agents seized two pounds of methamphetamine and a slew of ghost guns and ammunition, according to court records. Nathan Solis, Los Angeles Times, 6 June 2024 But one vehicle allegedly sent by the trafficking group — prosecutors said it was inspected after its license plate set off an alert that George couldn’t override without raising suspicion — contained 223 pounds of methamphetamine and 13 pounds of fentanyl. Alex Riggins, San Diego Union-Tribune, 4 June 2024 The arrest report says on Feb. 29, police found 4.1 grams of methamphetamine in a sandwich bag in Gunn’s car after stopping her for making a right turn out of the left turn lane when leaving a Walmart. David J. Neal, Miami Herald, 2 June 2024 See all Example Sentences for methamphetamine 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'methamphetamine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of methamphetamine was in 1949

Dictionary Entries Near methamphetamine

Cite this Entry

“Methamphetamine.” Dictionary, Merriam-Webster, Accessed 22 Jun. 2024.

Kids Definition


meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn How to pronounce methamphetamine (audio)
: a drug derived from amphetamine that is often used illegally as a stimulant of the central nervous system

Medical Definition


meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn, ˌmeth-əm-, -mən How to pronounce methamphetamine (audio)
: an amine C10H15N that is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit disorder and obesity and that is often abused illicitly as a stimulant

called also meth, methedrine, methylamphetamine, speed

More from Merriam-Webster on methamphetamine

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