metformin

noun

met·​for·​min met-ˈfȯr-mən How to pronounce metformin (audio)
: a drug used in the form of its hydrochloride C4H11N5·HCl especially to treat type 2 diabetes

Examples of metformin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Mayo Clinic says metformin is generally safe, but can cause digestive side effects and vitamin B12 deficiency in some patients. Khloe Quill, FOXNews.com, 10 Feb. 2026 Key Takeaways For people with type 2 diabetes, berberine lowers blood sugar as effectively as standard diabetes medication Glucophage (metformin). Megan Nunn, Verywell Health, 14 Jan. 2026 Additionally, medications like metformin and GLP-1s can also be very helpful. Helen Carefoot, Flow Space, 5 Dec. 2025 In addition to lifestyle changes, treatments include insulin, metformin, and newer medications like GLP-1s. Emily Kay Votruba, EverydayHealth.com, 16 Sep. 2025 See All Example Sentences for metformin

Word History

Etymology

methyl + -formin (as in phenformin, an earlier antidiabetic drug)

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of metformin was in 1961

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Cite this Entry

“Metformin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metformin. Accessed 21 Feb. 2026.

Medical Definition

metformin

noun
met·​for·​min met-ˈfȯr-mən How to pronounce metformin (audio)
: an antidiabetic drug used in the form of its hydrochloride C4H11N5·HCl especially to treat type 2 diabetes in patients unresponsive to or intolerant of approved sulfonylurea drugs

Note: Trademarks for preparations containing metformin include Glucophage, Glucovance, Invokamet, Janumet, Jentadueto, and Kombiglyze.

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