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metformin

noun

met·​for·​min met-ˈfȯr-mən How to pronounce metformin (audio)
: a drug used in the form of its hydrochloride C4H11N5·HCl especially to treat type 2 diabetes

Examples of metformin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The researchers said future studies should explore how to preserve the benefits of both treatments, and the Rutgers team is now testing whether metformin interacts differently with resistance or strength training and whether adjusting dosage or timing could reduce the effect. Deirdre Bardolf, FOXNews.com, 15 Nov. 2025 Type 2 diabetes is commonly treated with metformin, a daily oral medication, and could be accompanied by insulin therapy. Caroline C. Boyle, USA Today, 3 Nov. 2025 This can include oral medicines, such as metformin, or injectable medicines, such as Ozempic (semaglutide). Karen Berger, Verywell Health, 1 Oct. 2025 In addition to lifestyle changes, treatments include insulin, metformin, and newer medications like GLP-1s. Emily Kay Votruba, EverydayHealth.com, 16 Sep. 2025 See All Example Sentences for metformin

Word History

Etymology

methyl + -formin (as in phenformin, an earlier antidiabetic drug)

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of metformin was in 1961

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Cite this Entry

“Metformin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metformin. Accessed 3 Dec. 2025.

Medical Definition

metformin

noun
met·​for·​min met-ˈfȯr-mən How to pronounce metformin (audio)
: an antidiabetic drug used in the form of its hydrochloride C4H11N5·HCl especially to treat type 2 diabetes in patients unresponsive to or intolerant of approved sulfonylurea drugs

Note: Trademarks for preparations containing metformin include Glucophage, Glucovance, Invokamet, Janumet, Jentadueto, and Kombiglyze.

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