metabolite

noun

me·​tab·​o·​lite mə-ˈta-bə-ˌlīt 

1

: a product of metabolism

2

: a substance essential to the metabolism of a particular organism or to a particular metabolic process

Examples of metabolite in a Sentence

Recent Examples on the Web

These 59 had normal ADA enzyme levels and detoxified metabolites. —New Atlas, 16 Oct. 2025

Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone–receptor activation. —Hannah Millington, MSNBC Newsweek, 10 Oct. 2025

These microbes react with the air and rock through photosynthesis and respiration to produce organic molecules called metabolites. —Chris Impey, The Conversation, 23 Sep. 2025

Scientists tested more than 300 combinations of growth factors, small molecules, and metabolites to develop the cells of Nicobar pigeons, the closest relative to the dodo. —Reed Albergotti, semafor.com, 19 Sep. 2025

Word History

Etymology

metabol(ic) or metabol(ism) + -ite entry 1

First Known Use

1877, in the meaning defined at sense 1

Rhymes for metabolite

• actinolite
• adipocyte
• amphibolite
• anorthosite
• anthophyllite
• aragonite
• carbonatite
• cassiterite
• cristobalite
• crocidolite
• diatomite
• dithionite

Kids Definition

metabolite

noun

me·​tab·​o·​lite mə-ˈtab-ə-ˌlīt 

1

: a substance produced by metabolism

2

: a substance essential to a process of metabolism

Medical Definition

metabolite

noun

me·​tab·​o·​lite -ˌlīt 

1

: a product of metabolism:

a

: a metabolic waste usually more or less toxic to the organism producing it : excretion

b

: a product of one metabolic process that is essential to another such process in the same organism

c

: a metabolic waste of one organism that is markedly toxic to another : antibiotic

2

: a substance essential to the metabolism of a particular organism or to a particular metabolic process