mes·​ca·​line | \ ˈme-skə-lən How to pronounce mescaline (audio) , ˈme-skə-ˌlēn \

Definition of mescaline

: a hallucinatory crystalline alkaloid C11H17NO3 that is the chief active principle in peyote buttons

Examples of mescaline in a Sentence

Recent Examples on the Web Some 20th-century psychiatrists thought mescaline might unlock the mechanism of schizophrenia. The Economist, "A mind-bending history of mescaline," 28 June 2019 Weissberg and his companion, their perceptions enhanced by a mescaline diet, didn’t stick around for Sunday’s program. Charlie Brennan, The Denver Post, "50 years on, Woodstock memories still glow for those who were there," 10 Aug. 2019 Carlos Santana famously played Woodstock while tripping out of his mind on mescaline. Corbin Reiff, Billboard, "Recasting Woodstock's Original Lineup With 2019 Artists," 13 Aug. 2019 Antonin Artaud worked mescaline’s effects into surrealism, Jean-Paul Sartre into existentialism. The Economist, "A mind-bending history of mescaline," 28 June 2019 There was one night, again at Spahn’s, where everybody took mega doses of acid and probably some mescaline or something else mixed in with it. Win Mccormack, The New Republic, "The Manson Girl Who Got Away," 29 July 2019 Day’s theory is that Manson may have wanted money from Leno, a grocery-store-chain owner who liked to gamble, to pay off the Straight Satans, who were still angry about getting their money back for the bad mescaline. Olivia B. Waxman, Time, "Why Did the Manson Family Kill Sharon Tate? Here’s the Story Charles Manson Told the Last Man Who Interviewed Him," 26 July 2019 In the front of the building, next to the sidewalk on busy Telegraph Avenue, grew San Pedro cacti, which contain the hallucinogen mescaline. Hailey Branson-potts,, "How a trip on magic mushrooms helped decriminalize psychedelic plants in a California city," 22 June 2019 Peyote contains mescaline, which has historically been used in religious ceremonies by Native Americans. Dana Burke, Houston Chronicle, "Katy man allegedly caught growing peyote, marijuana in his home," 12 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'mescaline.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of mescaline

1896, in the meaning defined above

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Time Traveler for mescaline

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The first known use of mescaline was in 1896

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Statistics for mescaline

Last Updated

9 Jan 2020

Cite this Entry

“Mescaline.” Dictionary, Merriam-Webster, Accessed 28 Feb. 2020.

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How to pronounce mescaline (audio)

English Language Learners Definition of mescaline

: a drug that comes from a cactus and that makes people see things that are not real


mes·​ca·​line | \ ˈmes-kə-lən How to pronounce mescaline (audio) , -ˌlēn How to pronounce mescaline (audio) \

Medical Definition of mescaline

: a hallucinatory crystalline alkaloid C11H17NO3 that is the chief active principle in peyote buttons

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