melanoma

noun

mel·​a·​no·​ma ˌme-lə-ˈnō-mə 

plural melanomas also melanomata ˌme-lə-ˈnō-mə-tə 

1

: a tumor containing dark pigment

2

: a highly malignant tumor that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

Examples of melanoma in a Sentence

Recent Examples on the Web

To date, there are studies into how the procedure could benefit treatment of autism spectrum disorder, alcohol use disorder, obesity, melanoma and cancer. —New Atlas, 28 Nov. 2025

She was previously diagnosed with breast cancer in 2023 and melanoma, a type of skin cancer, in 2024. —Jason Pham, StyleCaster, 23 Nov. 2025

In fact, Nussbaum says that pilots and cabin crew experience about twice the incidence of melanoma as the general population. —Iona Brannon, Travel + Leisure, 2 Nov. 2025

The majority of melanoma cases are attributable to UV exposure. —Staff Author, PEOPLE, 30 Oct. 2025

Word History

Etymology

melan- (in melanosis, melanotic) + -oma

First Known Use

1838, in the meaning defined at sense 1

Phrases Containing melanoma

• malignant melanoma

Rhymes for melanoma

• ambystoma
• atheroma
• carcinoma
• coloboma
• granuloma
• haematoma
• hamartoma
• hemangioma
• hematoma
• hepatoma
• hybridoma
• myeloma

Kids Definition

melanoma

noun

mel·​a·​no·​ma ˌmel-ə-ˈnō-mə 

plural melanomas also melanomata -mət-ə 

: a usually malignant tumor containing dark pigment

Medical Definition

melanoma

noun

mel·​a·​no·​ma ˌmel-ə-ˈnō-mə 

plural melanomas also melanomata -mət-ə 

1

: a benign or malignant skin tumor containing dark pigment

2

: a tumor of high malignancy that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

called also malignant melanoma, melanocarcinoma, melanoepithelioma, melanosarcoma