: any of a breed of very large massive powerful smooth-coated dogs that are apricot, fawn, or brindle and are often used as guard dogs
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Located in the elegant Evasion Mont Blanc, there are nearly 250 miles of slopes spread over four mastiffs to ski here, and well, to plot.—Kathleen Rellihan, Outside, 5 Sep. 2025 Cane Corsos, an ancient Italian mastiff breed, are renowned for their sheer size and protective instincts.—Melissa Fleur Afshar, MSNBC Newsweek, 2 Sep. 2025 The Guinness World Record for most puppies in one litter belongs to Tia, a Neapolitan mastiff who gave birth to 24 puppies on Nov. 29, 2004, in Manea, U.K.—Kimberlee Speakman, People.com, 2 Sep. 2025 Deebo weighs 115 pounds and is a mix of American pit bull, St. Bernard, Great Dane and mastiff, Pitlanish said.—Eric D. Lawrence, USA Today, 12 Aug. 2025 See All Example Sentences for mastiff
Word History
Etymology
Middle English mastif, from Medieval Latin mastivus, from Vulgar Latin *masuetivus, from Latin mansuetus tame — more at mansuetude
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