lysergic acid


ly·​ser·​gic acid lə-ˈsər-jik- How to pronounce lysergic acid (audio) (ˌ)lī- How to pronounce lysergic acid (audio)
: a crystalline acid C16H16N2O2 from ergotic alkaloids
also : lsd

Example Sentences

Recent Examples on the Web It’s created from the lysergic acid found in ergot, which is a fungus that infects rye. Stav Dimitropoulos, SELF, 29 Apr. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'lysergic acid.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


lysergic from lys- (in hydrolysis) + erg(ot) + -ic entry 1

Note: Word introduced by the American biochemist Walter A. Jacobs (1883-1967) and chemist Lyman C. Craig (1906-74) in "The ergot alkaloids II. The degradation of ergotinine with alkali. Lysergic acid," Journal of Biological Chemistry, vol. 104, no. 3 (March 1, 1934), pp. 547-51.

First Known Use

1934, in the meaning defined above

Time Traveler
The first known use of lysergic acid was in 1934

Dictionary Entries Near lysergic acid

Cite this Entry

“Lysergic acid.” Dictionary, Merriam-Webster, Accessed 25 Mar. 2023.

Medical Definition

lysergic acid

ly·​ser·​gic acid lə-ˌsər-jik- How to pronounce lysergic acid (audio) (ˌ)lī- How to pronounce lysergic acid (audio)
: a crystalline acid C16H16N2O2 that is an ergotic alkaloid
also : lsd

More from Merriam-Webster on lysergic acid

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