lu·​pus | \ ˈlü-pəs \

Definition of lupus

1 : any of several diseases characterized by skin lesions especially : systemic lupus erythematosus sense 2
2 Lupus, astronomy : a southern constellation that is visible between the constellations of Scorpius and Centaurus and that is represented by the figure of a wolf Above Lupus lies Scorpius, one of the few constellations whose star pattern actually suggests the object that it is named for. In the myths, the scorpion was assigned by Artemis, the hunting goddess, to kill Orion, far across the sky.— Don Moser

Examples of lupus in a Sentence

Recent Examples on the Web

More on chronic illness: Watch how this lupus advocate finds beauty in illness: Follow Allure on Instagram and Twitter, or subscribe to our newsletter for daily beauty stories delivered right to your inbox. Ilana Kaplan, Allure, "Selma Blair Reveals She Has Multiple Sclerosis in Heartfelt Post," 22 Oct. 2018 Last summer, Selena underwent a life-saving kidney transplant to help treat her lupus. Hanna Lustig, Teen Vogue, "11 Selena Gomez Facts You Might Not Have Known," 22 July 2018 Doctors tested Emily for everything from bulging disks and hypothyroidism to lupus and multiple sclerosis — all came back negative. Leslie Goldman, Woman's Day, "More Women Have Fibromyalgia Than Breast Cancer," 10 Sep. 2017 His mother has suffered from lupus, a chronic autoimmune disease, for the past 13 years, and has Sjogren’s syndrome and arthritis, both chronic diseases. Austin Horn, San Antonio Express-News, "With ACA under attack, a family racked by illness wonders what will happen to their health coverage," 13 July 2018 Soon after losing his two best friends to lymphoma and lupus, in Spring 2016, Henry’s beloved mother, Willow Dean Kearse, was killed in a car accident. Jenna Marotta, Vogue, "Brian Tyree Henry Still Roots for the Underdog," 23 Nov. 2018 There are many other health conditions that can cause frequent proteinuria, according to the Mayo Clinic, like pregnancy, preeclampsia, rheumatoid arthritis, lupus, heart disease, and sickle cell anemia. Korin Miller, SELF, "4 Causes Behind Urine So Foamy It Could Top a Beer," 4 Oct. 2018 Since receiving a kidney transplant last summer to treat her lupus, Selena Gomez has been incredibly open about the procedure’s effects on her life, from teaching her to love her body to bringing her closer to her friend and donor Francia Raísa. Tess Garcia, Teen Vogue, "Selena Gomez Addresses the Widespread Impact of Her Kidney Transplant," 18 Aug. 2018 And children infected with EBV are up to 50 times more likely to eventually develop lupus, which currently has no cure. Roni Dengler, Science | AAAS, "How the virus behind ‘kissing disease’ may increase your risk for autoimmune diseases like lupus," 16 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'lupus.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of lupus

14th century, in the meaning defined at sense 1

History and Etymology for lupus

Middle English, from Medieval Latin, from Latin, wolf

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Dictionary Entries near lupus


lupulic acid



lupus erythematosus



Statistics for lupus

Last Updated

27 Jan 2019

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The first known use of lupus was in the 14th century

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English Language Learners Definition of lupus

medical : a disease that affects the nervous system, joints, and skin


lu·​pus | \ ˈlü-pəs \

Medical Definition of lupus

: any of several diseases (as lupus vulgaris or systemic lupus erythematosus) characterized by skin lesions

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Rhyming Dictionary: Words that rhyme with lupus

Britannica English: Translation of lupus for Arabic Speakers

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