lu·​pus | \ˈlü-pəs \

Definition of lupus 

1 : any of several diseases characterized by skin lesions especially : systemic lupus erythematosus sense 2

2 Lupus , astronomy : a southern constellation that is visible between the constellations of Scorpius and Centaurus and that is represented by the figure of a wolf Above Lupus lies Scorpius, one of the few constellations whose star pattern actually suggests the object that it is named for. In the myths, the scorpion was assigned by Artemis, the hunting goddess, to kill Orion, far across the sky.— Don Moser

Examples of lupus in a Sentence

Recent Examples on the Web

When the lupus caused Lori Kloepping's kidneys to shut down last year, McGhee was there to offer up one of hers — a decision that not only saved her mom, but a stranger as well. Andy Marso, kansascity, "Another historic chain: Research Medical Center transplants four kidneys in two days," 22 June 2018 More than 40 similar therapies are in the works for diseases as varied as lupus, lung infections, and cancer. Mitch Leslie, Science | AAAS, "Mini-antibodies discovered in sharks and camels could lead to drugs for cancer and other diseases," 10 May 2018 Hundreds of lupus survivors, friends and families are expected to take part in the walk at 10 a.m. Saturday, Aug. 11, starting at the Riverwalk’s Grand Pavilion, 912 Honorary Sindt Memorial Court. Michelle Mullins, Naperville Sun, "Naperville News Digest," 29 June 2018 About a year ago, Selena Gomez underwent a kidney transplant due to complications from her lupus diagnosis. Emily Wang, Glamour, "Selena Gomez Says She's 'Stepped Back a Bit' Since Her Kidney Transplant," 29 June 2018 After 53 days in the hospital and multiple complications, including pneumonia and blood clots, doctors diagnosed Yani with lupus, an autoimmune disorder. Daniel Wilson, sacbee, "Sacramento Make-A-Wish teen ‘touched and grateful’ to be honorary Kings dancer," 11 July 2018 At times, Salas’ father couldn’t obtain coverage under his policy for his wife’s chemo infusions for her lupus treatment. Austin Horn, San Antonio Express-News, "With ACA under attack, a family racked by illness wonders what will happen to their health coverage," 13 July 2018 That day, Brown said temperatures reached over 100 degrees, causing scars from her lupus – an autoimmune disease Brown said she's lived with for 15 years – to flare. Madeline Farber, Fox News, "California woman denied manicure over lupus scars, she says: 'I've never felt more like a leper'," 12 July 2018 There will be crafts and face painting for kids, a photo booth and information about lupus. Michelle Mullins, Naperville Sun, "Naperville News Digest," 29 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'lupus.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of lupus

14th century, in the meaning defined at sense 1

History and Etymology for lupus

Middle English, from Medieval Latin, from Latin, wolf

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Dictionary Entries near lupus


lupulic acid



lupus erythematosus



Statistics for lupus

Last Updated

20 Oct 2018

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The first known use of lupus was in the 14th century

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English Language Learners Definition of lupus

medical : a disease that affects the nervous system, joints, and skin


lu·​pus | \ˈlü-pəs \

Medical Definition of lupus 

: any of several diseases (as lupus vulgaris or systemic lupus erythematosus) characterized by skin lesions

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something that serves to warn or remind

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