lu·​pus ˈlü-pəs How to pronounce lupus (audio)
: any of several diseases characterized by skin lesions
Lupus astronomy : a southern constellation that is visible between the constellations of Scorpius and Centaurus and that is represented by the figure of a wolf
Above Lupus lies Scorpius, one of the few constellations whose star pattern actually suggests the object that it is named for. In the myths, the scorpion was assigned by Artemis, the hunting goddess, to kill Orion, far across the sky.Don Moser

Examples of lupus in a Sentence

Recent Examples on the Web O'Connor, who died in 1964, was also diagnosed with lupus during this time in her life. Esme Mazzeo, Peoplemag, 12 Apr. 2024 In the soon-to-start lupus study, Caribou intends to use HLA partial matching between patients and the donor T cells that could improve outcomes, the company said. Meghana Keshavan, STAT, 5 Apr. 2024 Over 80 autoimmune diseases exist worldwide, including rheumatoid arthritis, celiac disease, lupus, Type 1 diabetes, multiple sclerosis, SIBO, and inflammatory bowel disease. Dr. Brittany Chambers, Forbes, 27 Mar. 2024 Kelly’s lupus diagnosis brought her closer to Sharon Kelly was diagnosed with lupus in 2007. Nicole Briese, Peoplemag, 17 Mar. 2024 Sharma is one of at least 80 million people across the United States who suffer from hair loss due to various medical conditions such as alopecia areata, lupus and cancer patients receiving chemotherapy treatment. Ryan MacAsero, The Mercury News, 10 Mar. 2024 If the immune system is an army, then those with conditions like lupus, multiple sclerosis, or rheumatoid arthritis are often fighting a never-ending war of friendly fire. Theresa Gaffney, STAT, 21 Feb. 2024 Conditions like diabetes, lupus, and high blood pressure can damage the kidneys over time, reducing their ability to function. Nathaniel Scharping, Discover Magazine, 16 Feb. 2024 Neonatal lupus is a rare condition that is passed from a pregnant woman to her infant. Melissa Rudy, Fox News, 14 Feb. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'lupus.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


Middle English, from Medieval Latin, from Latin, wolf

First Known Use

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of lupus was in the 14th century

Dictionary Entries Near lupus

Cite this Entry

“Lupus.” Dictionary, Merriam-Webster, Accessed 18 Apr. 2024.

Medical Definition


lu·​pus ˈlü-pəs How to pronounce lupus (audio)
: any of several diseases (as lupus vulgaris or systemic lupus erythematosus) characterized by skin lesions

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