light chain

noun

: either of the two smaller of the four polypeptide chains comprising antibodies compare heavy chain

Example Sentences

Recent Examples on the Web Two of the key markers — kappa/lambda light chain and of monoclonal protein in the bone marrow — are down from wildly high to within sight of normal. Jeff Metcalfe, The Arizona Republic, 27 Nov. 2021 Neurofilament light chain, for example, is a structural protein that maintains neurons' axons, which transmit signals to other neurons. ABC News, 7 Nov. 2021 The Alzheimer’s Disease Neuroimaging Initiative recently reported that measurements of plasma neurofilament-light chain (NfL) can predict the trajectory of decline. Sam Gandy, STAT, 17 June 2021 Earlier this year, a separate group of researchers at WUSTL published work showing that the levels of a protein called neurofilament light chain in the blood could predict brain damage. Katherine Ellen Foley, Quartz, 1 Aug. 2019 The mini-antibodies retain roughly the same shape but are missing the light chains. Mitch Leslie, Science | AAAS, 10 May 2018 Earlier this year, a separate group of researchers at WUSTL published work showing that the levels of a protein called neurofilament light chain in the blood could predict brain damage. Katherine Ellen Foley, Quartz, 1 Aug. 2019 Like the camel versions, the shark antibody was smaller than the regular variety and lacked light chains. Mitch Leslie, Science | AAAS, 10 May 2018 The mini-antibodies retain roughly the same shape but are missing the light chains. Mitch Leslie, Science | AAAS, 10 May 2018 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'light chain.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1962, in the meaning defined above

Time Traveler
The first known use of light chain was in 1962

Dictionary Entries Near light chain

Cite this Entry

“Light chain.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/light%20chain. Accessed 4 Dec. 2022.

Medical Definition

light chain

noun

: either of the two smaller of the four polypeptide chains that are subunits of antibodies

called also L chain

compare heavy chain

More from Merriam-Webster on light chain

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