li·​do·​caine | \ ˈlī-də-ˌkān How to pronounce lidocaine (audio) \

Definition of lidocaine

: a crystalline compound C14H22N2O that is used in the form of its hydrochloride as a local anesthetic and as an antiarrhythmic agent

Examples of lidocaine in a Sentence

Recent Examples on the Web Ultimately, Febles, who is an employee relations manager for the urgent care company MedRite, was given antibiotics and a single oxycodone pill and sent home with a lidocaine topical solution. Benjamin Ryan, NBC News, 6 July 2022 The comment was made after two Baffert horses that tested positive for lidocaine in Arkansas were restored as winners after it was determined the substance was ingested because of contamination as horses in other barns also tested positive. John Cherwaspecial Contributor, Los Angeles Times, 21 June 2022 Both menthol and lidocaine directly alleviate the itchiness of a bug bite. Sara Coughlin, SELF, 11 May 2022 Your doctor can prescribe a cream with lidocaine or another anesthetic to relieve the pain until the tiny tear heals. Rozalynn S. Frazier, SELF, 10 Mar. 2022 Charlatan and Gamine tested positive for lidocaine on Arkansas Derby day. John Cherwa, Los Angeles Times, 9 May 2021 Many of these—such as cognitive behavioral therapy, massage therapy, acupuncture, lidocaine injections, and nerve blocks—are often not covered by insurance. Laura Weiss, The New Republic, 17 Dec. 2021 For a distinct or defined area, a lidocaine patch can be extraordinarily effective. Dr. Keith Roach, oregonlive, 22 Oct. 2021 Topical anesthetics like lidocaine creams or cold sprays can be applied to the skin at the injection site prior to the shot to reduce pain, said Dr. Diana Bottari, a pain specialist with Advocate Aurora Health. Angie Leventis Lourgos,, 22 Oct. 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'lidocaine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of lidocaine

circa 1949, in the meaning defined above

History and Etymology for lidocaine

acetanilid + -o- + -caine

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The first known use of lidocaine was circa 1949

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Last Updated

1 Aug 2022

Cite this Entry

“Lidocaine.” Dictionary, Merriam-Webster, Accessed 7 Aug. 2022.

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More Definitions for lidocaine


li·​do·​caine | \ ˈlīd-ə-ˌkān How to pronounce lidocaine (audio) \

Medical Definition of lidocaine

: a crystalline compound C14H22N2O used as a local anesthetic often in the form of its hydrochloride C14H22N2O·HCl

called also lignocaine

— see xylocaine

More from Merriam-Webster on lidocaine Encyclopedia article about lidocaine


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