lidocaine

noun

li·​do·​caine ˈlī-də-ˌkān 

: a crystalline compound C₁₄H₂₂N₂O that is used in the form of its hydrochloride as a local anesthetic and as an antiarrhythmic agent

Examples of lidocaine in a Sentence

Recent Examples on the Web

Epinephrine, or adrenaline, is added to lidocaine and other dental numbing solutions to shrink blood vessels, reduce bleeding and prolong numbness. —Sandee Lamotte, CNN Money, 29 Dec. 2025

Ross recommends applying a cold compress and taking oral antihistamines for itching and over-the-counter pain relievers or a topical lidocaine cream for pain. —Taryn White, Travel + Leisure, 20 Dec. 2025

The cream contains lidocaine and is rubbed into muscles to ease pain. —Charlotte Phillipp, PEOPLE, 20 Dec. 2025

When asked about her pre-runway show rituals, Graham first showed off her fuzzy socks, then excitedly whipped out a can of lidocaine spray and showed it to camera. —Ariana Yaptangco, Glamour, 25 Nov. 2025

Word History

Etymology

acetanilid + -o- + -caine

First Known Use

circa 1949, in the meaning defined above

Rhymes for lidocaine

• aeroplane
• appertain
• ascertain
• capitaine
• cassegrain
• cellophane
• chatelaine
• counterpane
• entertain
• gethsemane
• halothane
• hurricane

Medical Definition

lidocaine

noun

li·​do·​caine ˈlīd-ə-ˌkān 

: a crystalline compound C₁₄H₂₂N₂O used as a local anesthetic often in the form of its hydrochloride C₁₄H₂₂N₂O·HCl

called also lignocaine

see xylocaine