leukodystrophy

noun
leu·​ko·​dys·​tro·​phy | \ ˌlü-kō-ˈdi-strə-fē How to pronounce leukodystrophy (audio) \
plural leukodystrophies

Definition of leukodystrophy

: any of several genetically determined diseases characterized by progressive degeneration of myelin in the brain, spinal cord, and peripheral nerves

Examples of leukodystrophy in a Sentence

Recent Examples on the Web After further testing, he was diagnosed with metachromatic leukodystrophy in July of this year. Lisa Schencker, chicagotribune.com, "No. No. No. No. No. An insurer rejected out-of-state treatment for a 4-year-old’s rare disease five times. It relented, but why is getting an OK so hard?," 15 Nov. 2019 Doctors knew Massimo suffered from a type of leukodystrophy, a genetic disorder of the central nervous system that destroys the brain’s white matter. Wired, "One Scientist’s Quest to Bring DNA Sequencing to Every Sick Kid," 30 Aug. 2019 Ollie passed away in December due to a rare genetic disorder, leukodystrophy, which affects the neural anatomy of a person in a variety of ways. Joe Mario Pedersen, orlandosentinel.com, "Disney rejects father’s requests to put Spider-Man on son’s grave: report," 5 July 2019 Most children with metachromatic leukodystrophy don’t survive beyond their 8th birthday. Vibhav Rangarajan, STAT, "The ‘cruel joke’ of compassionate use and right to try: Pharma companies don’t have to comply," 5 June 2018 Children with the most severe form of metachromatic leukodystrophy develop symptoms like trouble walking or poor muscle tone before the age of 30 months. Vibhav Rangarajan, STAT, "The ‘cruel joke’ of compassionate use and right to try: Pharma companies don’t have to comply," 5 June 2018 Their daughter Beatrice had leukodystrophy, a progressive disease of the brain that left her unable to walk or talk. Jim Stingl, Milwaukee Journal Sentinel, "Stingl: 'Victory in motion' — Widow with 9 kids graduates from Mount Mary and hopes to help other women," 1 June 2018 In 2013, Conte acted as the lawyer for the family of Sofia de Barros, a 4-year-old girl suffering from metachromatic leukodystrophy, an incurable disease of the nervous system. Luca Tancredi Barone, Science | AAAS, "Italy’s new prime minister defended discredited stem cell therapy," 24 May 2018 That was the day a neurologist at Children’s Hospital of Philadelphia explained how my 2-year-old daughter, Cal, had late infantile-onset metachromatic leukodystrophy (MLD). Maria Kefalas, STAT, "How much would you pay for the miracle of gene therapy?," 3 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'leukodystrophy.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of leukodystrophy

1960, in the meaning defined above

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The first known use of leukodystrophy was in 1960

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Last Updated

20 Nov 2019

Cite this Entry

“Leukodystrophy.” The Merriam-Webster.com Dictionary, Merriam-Webster Inc., https://www.merriam-webster.com/dictionary/leukodystrophy. Accessed 9 December 2019.

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More Definitions for leukodystrophy

leukodystrophy

noun
leu·​ko·​dys·​tro·​phy
variants: or chiefly British leucodystrophy \ ˌlü-​kō-​ˈdis-​trə-​fē How to pronounce leucodystrophy (audio) \
plural leukodystrophies

Medical Definition of leukodystrophy

: any of several inherited diseases (as adrenoleukodystrophy) characterized by progressive degeneration of myelin in the brain, spinal cord, and peripheral nerves

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