: a general anesthetic that is administered intravenously and intramuscularly in the form of its hydrochloride C13H16ClNO·HCl and that is used illicitly usually by being inhaled in powdered form especially for the dreamlike or hallucinogenic state it produces

Note: Ketamine is also called Special K when used as a recreational drug

Examples of ketamine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Jane Doe’s alleged assault, which involved numerous substances including ketamine, took place later that night. — Rebekah Riess, CNN Money, 2 Oct. 2026 The actor Matthew Perry died in 2023 from the effects of ketamine. — Violet Jira, Washington Post, 1 Oct. 2026 Perry, who struggled with drugs and alcohol for much of his life, died in 2023 after taking too much ketamine and drowning in his hot tub. — Tony Maglio, HollywoodReporter, 29 Sep. 2026 Many children also reported taking ketamine for a year or more, meaning use of the drug may have begun at age 12 or younger. — Vanessa Etienne, PEOPLE, 23 Sep. 2026 See All Example Sentences for ketamine

Word History

Etymology

ket(one) + amine

First Known Use

1966, in the meaning defined above

Time Traveler
The first known use of ketamine was in 1966

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Cite this Entry

“Ketamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ketamine. Accessed 5 Oct. 2026.

Medical Definition

: a general anesthetic that is administered intravenously or intramuscularly in the form of its hydrochloride C13H16ClNO·HCl and that is used illicitly usually by being inhaled in powdered form especially for the dreamlike or hallucinogenic state it produces see special k
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