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kar·yo·some | \ ˈker-ē-ə-ˌsōm 
, ˈka-rē-\
, ˈka-rē-\Definition of karyosome
: a mass of chromatin in a cell nucleus that resembles a nucleolus
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karyosome
nounkar·yo·some | \ ˈkar-ē-ə-ˌsōm \
\Medical Definition of karyosome
: a mass of chromatin in a cell nucleus that resembles a nucleolus
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