1
: a narrow strip of land connecting two larger land areas
2
: a narrow anatomical part or passage connecting two larger structures or cavities
Examples of isthmus in a Sentence
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In 2003, a momentous discovery on the Ness of Brodgar, a narrow isthmus just north of Stenness, transformed perceptions of prehistoric Orkney.
—
Alex Ross, New Yorker, 24 Nov. 2025
The state Capitol building and the University of Wisconsin-Madison are located on an isthmus that runs between it and Lake Monona, a 5-square-mile lake to the east.
—CBS News, 20 Nov. 2025
The state Capitol building and the University of Wisconsin-Madison are located on an isthmus that runs between it and Lake Monona, a 5-square-mile (13-square-kilometer) lake to the east.
—Todd Richmond, Fortune, 19 Nov. 2025
As such, one lesson other Central American elites have drawn from his regime is that capitalism in the isthmus can thrive without democracy.
—Tim Brinkhof, JSTOR Daily, 8 Oct. 2025
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Alex Ross, New Yorker, 24 Nov. 2025
The state Capitol building and the University of Wisconsin-Madison are located on an isthmus that runs between it and Lake Monona, a 5-square-mile lake to the east.
—CBS News, 20 Nov. 2025
The state Capitol building and the University of Wisconsin-Madison are located on an isthmus that runs between it and Lake Monona, a 5-square-mile (13-square-kilometer) lake to the east.
—Todd Richmond, Fortune, 19 Nov. 2025
As such, one lesson other Central American elites have drawn from his regime is that capitalism in the isthmus can thrive without democracy.
—Tim Brinkhof, JSTOR Daily, 8 Oct. 2025
See All Example Sentences for isthmus
Cite this Entry
“Isthmus.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isthmus. Accessed 16 Dec. 2025.
Copy CitationKids Definition
isthmus
noun
isth·mus
ˈis-məs 
: a narrow strip of land connecting two larger land areas
Medical Definition
isthmus
noun
isth·mus
ˈis-məs
: a contracted anatomical part or passage connecting two larger structures or cavities: as
a
: an embryonic constriction separating the midbrain from the hindbrain
b
: the lower portion of the uterine corpus
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