1
: a narrow strip of land connecting two larger land areas
2
: a narrow anatomical part or passage connecting two larger structures or cavities
Examples of isthmus in a Sentence
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As such, one lesson other Central American elites have drawn from his regime is that capitalism in the isthmus can thrive without democracy.
—
Tim Brinkhof, JSTOR Daily, 8 Oct. 2025
We are connected to the Spanish mainland via two bridges and a natural isthmus, which has been in use since Roman times.
—Lisa Deaderick, San Diego Union-Tribune, 20 Sep. 2025
Where is Francesca Hong from? Hong is from Madison and still represents the city's isthmus area in the state Assembly.
—Hope Karnopp, jsonline.com, 17 Sep. 2025
He is shorn of his rakish mustache, and a scruffy isthmus sprouts at the crown of his receding hairline.
—Jessica Winter, New Yorker, 14 July 2025
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Tim Brinkhof, JSTOR Daily, 8 Oct. 2025
We are connected to the Spanish mainland via two bridges and a natural isthmus, which has been in use since Roman times.
—Lisa Deaderick, San Diego Union-Tribune, 20 Sep. 2025
Where is Francesca Hong from? Hong is from Madison and still represents the city's isthmus area in the state Assembly.
—Hope Karnopp, jsonline.com, 17 Sep. 2025
He is shorn of his rakish mustache, and a scruffy isthmus sprouts at the crown of his receding hairline.
—Jessica Winter, New Yorker, 14 July 2025
See All Example Sentences for isthmus
Cite this Entry
“Isthmus.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isthmus. Accessed 3 Nov. 2025.
Copy CitationKids Definition
isthmus
noun
isth·mus
ˈis-məs 
: a narrow strip of land connecting two larger land areas
Medical Definition
isthmus
noun
isth·mus
ˈis-məs
: a contracted anatomical part or passage connecting two larger structures or cavities: as
a
: an embryonic constriction separating the midbrain from the hindbrain
b
: the lower portion of the uterine corpus
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