1
: a narrow strip of land connecting two larger land areas
2
: a narrow anatomical part or passage connecting two larger structures or cavities
Examples of isthmus in a Sentence
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Panama Panama has long been a haven for expats, from mountain town Boquete to beach town Bocas del Toro to bustling Panama City, there’s truly something to suit everyone in this diverse isthmus.
—
Kathleen Peddicord, Forbes.com, 6 June 2025
Even after screwworms began creeping up the tail of the funnel recently, the anti-screwworm campaign had one last good chance of stopping them at a narrow isthmus in southern Mexico—after which the funnel grows dramatically wider.
—Sarah Zhang, The Atlantic, 27 May 2025
The latest screwworm detections in Oaxaca and Veracruz are just beyond the isthmus.
—Sarah Zhang, The Atlantic, 27 May 2025
Steamships laden with mail sailed from the East Coast to Panama, where the mail was taken off the ships, transported in canoes or on pack animals, and handed to another steamship waiting on the Pacific side of the isthmus.
—Hailey Branson-Potts, Los Angeles Times, 23 May 2025
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Kathleen Peddicord, Forbes.com, 6 June 2025
Even after screwworms began creeping up the tail of the funnel recently, the anti-screwworm campaign had one last good chance of stopping them at a narrow isthmus in southern Mexico—after which the funnel grows dramatically wider.
—Sarah Zhang, The Atlantic, 27 May 2025
The latest screwworm detections in Oaxaca and Veracruz are just beyond the isthmus.
—Sarah Zhang, The Atlantic, 27 May 2025
Steamships laden with mail sailed from the East Coast to Panama, where the mail was taken off the ships, transported in canoes or on pack animals, and handed to another steamship waiting on the Pacific side of the isthmus.
—Hailey Branson-Potts, Los Angeles Times, 23 May 2025
See All Example Sentences for isthmus
Cite this Entry
“Isthmus.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isthmus. Accessed 3 Jul. 2025.
Copy CitationKids Definition
isthmus
noun
isth·mus
ˈis-məs 
: a narrow strip of land connecting two larger land areas
Medical Definition
isthmus
noun
isth·mus
ˈis-məs
: a contracted anatomical part or passage connecting two larger structures or cavities: as
a
: an embryonic constriction separating the midbrain from the hindbrain
b
: the lower portion of the uterine corpus
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