insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This may help with insulin resistance and reduce the risk of developing type 2 diabetes.4 Research suggests that flaxseed may reduce the risk of certain types of cancer. Brittany Lubeck, Verywell Health, 27 Aug. 2025 However, its high carb content may be an issue for individuals with high blood sugar, insulin resistance, or those following low-carb diets. Jillian Kubala, Health, 19 Aug. 2025 Having too much glucose in your blood for an extended period of time can lead to insulin resistance, when your cells stop responding to insulin. Kaitlin Sullivan, Health, 7 Aug. 2025 Chlorogenic acids have also been shown to improve insulin resistance and reduce blood pressure. Sara Novak, Discover Magazine, 2 Aug. 2025 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 4 Sep. 2025.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!