insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

The authors note apoB is particularly valuable for patients with high triglycerides, insulin resistance or lower LDL-C levels, where traditional cholesterol numbers can be misleading. — Samantha Agate, Kansas City Star, 26 June 2026

Certain metabolic issues such as insulin resistance, where the body’s cells stop responding properly to insulin, may also block semaglutide’s actions. — Nadine Wehida, Scientific American, 25 June 2026

People with diabetes or insulin resistance may want to stick with unflavored powder or low-sugar capsules. — Samantha Agate, Miami Herald, 24 June 2026

Excessive intake of honey over time may lead to insulin resistance, which can cause blood sugar to spike after meals and snacks. — Brittany Lubeck, Verywell Health, 23 June 2026

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes