insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Research shows lifting weights can improve insulin resistance, reduce inflammation, and improve heart health. —Jakob Roze, Health, 31 Dec. 2025

Key Takeaways Eating fast food every day can drive weight gain, insulin resistance, and higher risks for type 2 diabetes and heart disease. —Anna Giorgi, Verywell Health, 29 Dec. 2025

Mucosal cells in the tissue grow abnormally and propagate these maladaptive changes, locking in a dysfunctional pattern that drives cravings, weight gain, and insulin resistance. —Elie Dolgin, IEEE Spectrum, 29 Dec. 2025

That means that a decrease in estrogen (which occurs during perimenopause and menopause) can increase insulin resistance, which in turn can increase the risk of type 2 diabetes, inflammation and high blood sugar. —Helen Carefoot, Flow Space, 22 Dec. 2025

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes