insulin resistance


Definition of insulin resistance

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web Fat surrounding the abdominal organs, known as visceral fat, is associated with a litany of serious health problems, including insulin resistance, heart disease and high blood pressure. Lauren Caruba, San Antonio Express-News, "Can removing abdominal fat reverse Type 2 diabetes? San Antonio researchers are testing a new surgery to find out.," 30 Apr. 2021 Some of these consumer companies’ users will be at risk of developing diabetes, with emerging signs of insulin resistance. Katie Palmer, STAT, "Glucose monitors revolutionized diabetes care. Now digital health startups want to bring them to the masses," 18 Apr. 2021 Cocoa also reduces the effects of cortisol, a stress hormone that causes insulin resistance and potential weight gain. Angela Watson,, "Health benefits of cocoa powder," 22 Mar. 2021 The latter drug, however, raises insulin resistance and may therefore make hyperglycemia even worse. Claudia Wallis, Scientific American, "Unraveling the Complex Link Between COVID and Diabetes," 24 Feb. 2021 Isothiocyanates, one of the most prominent ingredients in Moringa extract, have been promote strong anti-obesity effects along with other benefits like better management of insulin resistance and sensitivity. Daily Health Reports, Chron, "Meticore Reviews (2021 Updated) Diet Pills Supplement with Real Ingredients or Side Effects?," 4 Feb. 2021 Scientists think cortisol, the stress hormone, may play a role -- cortisol increases insulin resistance, which adds to fat deposits. Sandee Lamotte, CNN, "Belly fat linked to early death, study finds," 23 Sep. 2020 Such inflammation is associated with chronic conditions, such as insulin resistance, higher glucose levels, diabetes, heart disease and fatty liver disease. Pam Moore, Washington Post, "Some trainers tout HIIT as the best way to burn belly fat. Here’s what science says.," 15 Dec. 2020 At the end of the month, the study found that their subjects’ blood pressure and weight went down, and their insulin resistance (which can be a marker for diabetes) improved by 25%. Molly Longman,, "Sober October: Can A Month Off From Alcohol Really Improve Your Life?," 1 Oct. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'insulin resistance.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of insulin resistance

1927, in the meaning defined above

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Time Traveler for insulin resistance

Time Traveler

The first known use of insulin resistance was in 1927

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Statistics for insulin resistance

Last Updated

6 May 2021

Cite this Entry

“Insulin resistance.” Dictionary, Merriam-Webster, Accessed 6 May. 2021.

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More Definitions for insulin resistance

insulin resistance


Medical Definition of insulin resistance

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes

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