insulin resistance


Definition of insulin resistance

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web Moreover, some studies suggest that a higher level associated with testosterone therapy can reduce cardiovascular risk factors, including insulin resistance that causes type 2 diabetes. Bryant Stamford, The Courier-Journal, 30 June 2022 Typically, excess body fatness, especially around the midsection, is the prime factor in insulin resistance. Bryant Stamford, The Courier-Journal, 7 July 2022 An elevated heart rate at night has been shown in prior studies to be a risk factor for future heart disease and early death, while higher blood sugar levels are a sign of insulin resistance, which can ultimately lead to type 2 diabetes. Sandee Lamotte, CNN, 22 June 2022 Fat in the hips and butt is not linked to chronic disease such as cardiovascular disease, diabetes and insulin resistance. Marisa Cohen, Good Housekeeping, 5 May 2022 Indeed, a growing body of evidence is finding that for some people, obesity may not be caused by overeating but by insulin resistance and hormonal issues — factors that are affected by the new class of weight loss drugs. Lauren Dunn, NBC News, 10 June 2022 Over time, insulin resistance can ultimately lead to Type 2 diabetes. Sandee Lamotte, CNN, 14 Mar. 2022 Allara reduces the difficult path to diagnosis from years to days, with their diagnostic tool which tests a wide range of hormonal and metabolic markers, such as thyroid levels and insulin resistance. Anna Haines, Forbes, 15 June 2022 People with diabetes, insulin resistance, metabolic syndrome, and other chronic health conditions tend to be less metabolically flexible. Christine Byrne, Outside Online, 30 May 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'insulin resistance.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of insulin resistance

1927, in the meaning defined above

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Time Traveler for insulin resistance

Time Traveler

The first known use of insulin resistance was in 1927

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Dictionary Entries Near insulin resistance

insulin-like growth factor

insulin resistance

insulin resistance syndrome

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Statistics for insulin resistance

Last Updated

10 Aug 2022

Cite this Entry

“Insulin resistance.” Dictionary, Merriam-Webster, Accessed 14 Aug. 2022.

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More Definitions for insulin resistance

insulin resistance


Medical Definition of insulin resistance

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes


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