inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

Substantial evidence links psychological stress to inflammation, barrier impairment and skin aging, which is why breakouts, sensitivity and dullness flare during hard weeks. — Samantha Agate, Miami Herald, 28 Sep. 2026

Now it is marketed for skin conditions, inflammation, muscle pain, weight loss, sleep, hair growth and cognitive function. — Hanna Wickes, Charlotte Observer, 28 Sep. 2026

Extra body weight is a risk factor for high blood sugar and fat buildup in the liver, which can impair function and cause inflammation. — Stephanie Anderson Witmer, HEALTH, 28 Sep. 2026

Many of these differences involved genes that play important roles in inflammation. — Isabella Backman, Hartford Courant, 28 Sep. 2026

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue