inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

Wine contains beneficial plant compounds called antioxidants that may reduce inflammation and support heart health—setting it apart from hard liquors. —Lindsey Desoto, Health, 15 Nov. 2025

This mask uses powerful light modes to reduce wrinkles, soothe inflammation, promote collagen production, and improve skin tone. —Izzy Baskette, PEOPLE, 15 Nov. 2025

Participants also saw less reduction in inflammation and fasting glucose levels. —Deirdre Bardolf, FOXNews.com, 15 Nov. 2025

The team also saw stronger activity in the NPR1 pathway, which supports blood vessel health and reduces harmful inflammation. —Aamir Khollam, Interesting Engineering, 14 Nov. 2025

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue