inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

One study found that inhaling menthol extract reduced inflammation and swelling in the nasal passages and other allergy signs. —Mark Gurarie, Verywell Health, 8 July 2025

There’s no one-size-fits-all approach, but with the right guidance and support, patients can cultivate strategies to alleviate pain, reduce inflammation and foster a fulfilling, active life despite their diagnosis. —Chloe Castleberry, Flow Space, 7 July 2025

Buxton landed on the injured list twice last year, once with knee inflammation and once with hip inflammation, during an otherwise strong season. —Betsy Helfand, Twin Cities, 6 July 2025

A day laborer with liver inflammation who works long hours in construction, often seven days a week, and who’s paid in cash. —Lindsay Ryan, The Atlantic, 5 July 2025

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue