inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

In melanoma patients, Keytruda treatment can result in fatigue, diarrhea, rash and inflammation of joints and muscles, as well as of healthy organs in some cases. — CNN Money, 21 Aug. 2026

Fried’s latest injury update came just as Carlos Rodon returned to the rotation from elbow inflammation. — Peter Chawaga, Forbes.com, 21 Aug. 2026

This nutritional profile means sauerkraut may help promote healthier digestion, reduce inflammation, and support the immune system. — Amanda Doyle, HEALTH, 21 Aug. 2026

People with atopic dermatitis also have an overactive immune system, which can trigger inflammation. — Ayren Jackson-Cannady, Allure, 20 Aug. 2026

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue