inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən How to pronounce inflammation (audio)
Synonyms of inflammationnext
1
: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue
2
: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation. inflammations of the throat and ears
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This bacterial strain also appeared to worsen inflammation during certain infections, making sepsis more severe. Angelica Stabile, FOXNews.com, 8 June 2026 The drugs may also dial down the inflammation that can drive cancer development—and might even act directly on tumors. Lori Youmshajekian, Scientific American, 8 June 2026 Researchers are studying whether blocking integrins could help combat inflammation in the brain by blocking immune cells from carrying HIV into the central nervous system. Smita S. Iyer, The Conversation, 8 June 2026 Ectoin is a buzzy skincare ingredient known for its ability to shield the skin from environmental stress and reduce and soothe inflammation. Essence Wiley, InStyle, 7 June 2026 See All Example Sentences for inflammation

Word History

First Known Use

15th century, in the meaning defined at sense 1

Time Traveler
The first known use of inflammation was in the 15th century

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Cite this Entry

“Inflammation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/inflammation. Accessed 9 Jun. 2026.

Kids Definition

inflammation

noun
in·​flam·​ma·​tion ˌin-flə-ˈmā-shən How to pronounce inflammation (audio)
1
: the act of inflaming : the state of being inflamed
2
: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun
in·​flam·​ma·​tion ˌin-flə-ˈmā-shən How to pronounce inflammation (audio)
: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue
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