inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, and pain and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue

2

: the act of inflaming : the state of being inflamed

Examples of inflammation in a Sentence

The drug is used to reduce inflammation.

inflammations of the throat and ears

Recent Examples on the Web

Minnesota Timberwolves All-Star Anthony Edwards will miss the next several games with inflammation in his right knee, with the team in the thick of the race for playoff position in the Western Conference. —CBS News, 17 Mar. 2026

Other potential mechanisms include increasing insulin production, increasing sodium excretion and decreasing inflammation. —Tara Haelle, Scientific American, 17 Mar. 2026

These should never be used at home due to the risk of infection, excessive inflammation, tissue damage and scarring. —Fiona Ward, Glamour, 17 Mar. 2026

And when fermented in the colon, soluble fiber produces short-chain fatty acids that support gut health and help control inflammation. —Sarah Garone, Health, 16 Mar. 2026

Word History

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing inflammation

• anti-inflammation

Rhymes for inflammation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

1

: the act of inflaming : the state of being inflamed

2

: a bodily response to injury in which heat, redness, pain, swelling, and more than the usual amount of blood are present in the area affected

Medical Definition

inflammation

noun

in·​flam·​ma·​tion ˌin-flə-ˈmā-shən 

: a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue