in·​do·​meth·​a·​cin | \ ˌin-dō-ˈme-thə-sən How to pronounce indomethacin (audio) \

Definition of indomethacin

: a nonsteroidal drug C19H16ClNO4 with anti-inflammatory, analgesic, and antipyretic properties used especially to treat painful inflammatory conditions (such as rheumatoid arthritis and osteoarthritis)

Examples of indomethacin in a Sentence

Recent Examples on the Web Ibuprofen, naproxen, indomethacin, and other NSAIDs are effective across a variety of common conditions, from acute musculoskeletal pain to chronic arthritis., "NSAIDs: How dangerous are they for your heart?," 23 Oct. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'indomethacin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of indomethacin

1963, in the meaning defined above

History and Etymology for indomethacin

indole + meth- + acetic acid + -in entry 1

Keep scrolling for more

Learn More about indomethacin

Time Traveler for indomethacin

Time Traveler

The first known use of indomethacin was in 1963

See more words from the same year

Statistics for indomethacin

Last Updated

19 Nov 2019

Cite this Entry

“Indomethacin.” The Dictionary, Merriam-Webster Inc., Accessed 22 November 2019.

Keep scrolling for more

More Definitions for indomethacin


in·​do·​meth·​a·​cin | \ ˌin-dō-ˈmeth-ə-sən How to pronounce indomethacin (audio) \

Medical Definition of indomethacin

: an NSAID C19H16ClNO4 with analgesic and antipyretic properties used especially to treat painful inflammatory conditions (as rheumatoid arthritis and osteoarthritis) — see indocin

More from Merriam-Webster on indomethacin Encyclopedia article about indomethacin

Comments on indomethacin

What made you want to look up indomethacin? Please tell us where you read or heard it (including the quote, if possible).


not agreeing with established beliefs

Get Word of the Day daily email!

Test Your Vocabulary

Name that Food Quiz

Spell It

Can you spell these 10 commonly misspelled words?

Bee Cubed

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!