in·​do·​meth·​a·​cin ˌin-dō-ˈme-thə-sən How to pronounce indomethacin (audio)
: a nonsteroidal drug C19H16ClNO4 with anti-inflammatory, analgesic, and antipyretic properties used especially to treat painful inflammatory conditions (such as rheumatoid arthritis and osteoarthritis)

Examples of indomethacin in a Sentence

Recent Examples on the Web NSAIDs can be purchased over-the-counter, such as naproxen, but generally, doctors will prescribe a clinical-strength version for ankylosing spondylitis patients, such as indomethacin., 26 Jan. 2022 This is usually accomplished with prescription-strength non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen, or indomethacin, per the Spondylitis Association of America. Colleen Stinchcombe,, 24 Jan. 2022 Researchers were quick to argue that this class-wide ban would cover substances that already exist as medicines, such as the anti-inflammatory drug indomethacin. Doug Johnson, Scientific American, 5 Jan. 2022 Some surgeons use a medication such as indomethacin or celecoxib (Celebrex), or even radiation therapy, to prevent HO in high-risk individuals. Dr. Keith Roach, oregonlive, 8 Aug. 2021 Turmeric is also known to lessen the effects of several other medications including aspirin, ibuprofen, acetaminophen and indomethacin. Stefani Sassos, Ms, Rdn, Cso, Good Housekeeping, 22 Apr. 2021 Krogan, who is also an investigator at the Gladstone Institute in San Francisco, stressed that the beneficial effect from indomethacin was found in a relatively small number of patients. Mark Johnson, Milwaukee Journal Sentinel, 15 Oct. 2020 Another possible solution may be to use a common painkiller called indomethacin. Mark Johnson, Milwaukee Journal Sentinel, 15 Oct. 2020 According to the American Migraine Foundation, over-the-counter pain relievers, such as aspirin, acetaminophen, ibuprofen, naproxen and indomethacin, can cause MOH when used 15 or more days per month. Sandee Lamotte, CNN, 26 May 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'indomethacin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


indole + meth- + acetic acid + -in entry 1

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of indomethacin was in 1963

Dictionary Entries Near indomethacin

Cite this Entry

“Indomethacin.” Dictionary, Merriam-Webster, Accessed 19 Apr. 2024.

Medical Definition


in·​do·​meth·​a·​cin ˌin-dō-ˈmeth-ə-sən How to pronounce indomethacin (audio)
: an NSAID C19H16ClNO4 with analgesic and antipyretic properties used especially to treat painful inflammatory conditions (as rheumatoid arthritis and osteoarthritis) see indocin

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