in vivo

adverb or adjective
in vi·​vo | \ in-ˈvē-(ˌ)vō How to pronounce in vivo (audio) , -ˈwē-(ˌ)wō \

Definition of in vivo

: in the living body of a plant or animal

Examples of in vivo in a Sentence

Recent Examples on the Web Molecular biologist Reza Kalhor started his lab (part computational, part molecular and experimental, studying in vivo barcoding) at Johns Hopkins University last October. Chris Wright, Wired, "The Remarkable Stuff Scientists Get Done as They Work From Home," 8 June 2020 Although studies are already underway with viral vectors that deliver new genes to certain tissues in people, in vivo gene therapy has only been used to modify blood stem cells in animal models of certain diseases. Jon Cohen, Science | AAAS, "NIH and Gates Foundation lay out ambitious plan to bring gene-based treatments for HIV and sickle cell disease to Africa," 23 Oct. 2019 These can be conducted in vitro (using cells in a laboratory dish) or in vivo (using an animal as a stand-in for humans). Los Angeles Times, "Why will it take so long to make a coronavirus vaccine that can prevent COVID-19?," 12 Mar. 2020 There are experimental antivirals that have been used in vitro and in vivo. Tanya Lewis, Scientific American, "Infectious Disease Expert Discusses What We Know about the New Chinese Virus," 22 Jan. 2020 So that will be in vitro and in vivo work in animals, and then validating that in human lactation studies. STAT, "How Europe is building a sweeping system to study medication safety in pregnant and lactating women," 21 June 2019 If a drug passes initial screening tests in vitro, researchers next test it in vivo in live animals to determine the effects of a new drug on a whole system instead of just one cell type at a time. Smithsonian, "How Putting Organs on Chips Could Revolutionize Medicine," 31 May 2018 On the question of whether CRISPR can be safely used in vivo, the stakes are high for many. Meghana Keshavan, STAT, "CRISPR paper that sent stocks tumbling is retracted," 30 Mar. 2018 If wider studies do, in fact, confirm that CCL11 can be used as a specific in vivo marker for CTE, then what? Jenny Vrentas,, "Diagnosing CTE: A Breakthrough Could Be Here ‘In the Next Five Years’," 27 Sep. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'in vivo.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of in vivo

1901, in the meaning defined above

History and Etymology for in vivo

New Latin, literally, in the living

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Time Traveler for in vivo

Time Traveler

The first known use of in vivo was in 1901

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Last Updated

27 Jun 2020

Cite this Entry

“In vivo.” Dictionary, Merriam-Webster, Accessed 15 Jul. 2020.

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More Definitions for in vivo

in vivo

adverb or adjective
in vi·​vo | \ in-ˈvē-(ˌ)vō How to pronounce in vivo (audio) \

Medical Definition of in vivo

1 : in the living body of a plant or animal in vivo synthesis of DNA microorganisms are not ordinarily destroyed in vivo by bacteriostatic drugsJournal of the American Medical Association
2 : in a real-life situation observing a patient's behavior in vivo

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